Hyaluronic acid was first used in medicine in mid 1980s. Currently, HA is the world’s most frequently used filler. It is among the natural chemical substances found in the skin and serves as a major structural component of extracellular space. When used in aesthetic medicine, hyaluronic acid is cross-linked which means it is subjected to a process aimed at prolonging its residence time in tissue.
Hyaluronic acid is used as a static facial wrinkle filler. Clinical effects start becoming noticeable within 24-48 h and the maximum effect occurs after 2 approximately weeks and lasts from 6 to 12 months. During this period, the filler is gradually degraded to carbon dioxide and water.
Mesolift is a method for facial skin rejuvenation using non-cross-linked hyaluronic acid. It is performed by numerous superficial needle insertions with a simultaneous injections on non-stabilized hyaluronic acid. Released from deposits, it significantly improves the hydration of the epidermis and gives the skin a radiant look.
Depending on the condition of the skin, 3-4 treatments need to be performed every 2 weeks, then 3 treatments every month and then follow-up treatments every 3-6 months.
